Targeted Protein Degraders: Trends, Challenges, and Solutions

Targeted Protein Degraders: Trends, Challenges, and Solutions

Since 2016, WuXi AppTec has built a comprehensive discovery platform focused on Targeted Protein Degraders (TPDs). Our platform enables research teams to investigate the complete TPD functional cycle, from binary and ternary complex formation and protein ubiquitination to degradation. Our end-to-end services encompass over 20 assay technologies, 10+ types of TPD molecules, and one-stop screening for proteins of interest (POI) and linkers using a bifunctional DNA-encoded library.

 

 

 

 

 

能力平台

化合物库

靶向蛋白降解剂

流动化学

反应条件筛选

计算化学

酶催化

分析纯化

化学合成

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