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Must Know Strategies for Targeted Covalent Inhibitor Synthesis

With advancements in drug design, there is resurging interest in drugs that form covalent bonds with their targets, often referred to as targeted covalent inhibitors (TCIs). Covalent drugs have the potential to provide enhanced potency and prolonged duration of action compared to non-covalent drugs.

WuXi AppTec’s Research Chemistry Services (RCS) offers a comprehensive discovery platform to support covalent chemistry. Our services include custom compound synthesis, analysis, and purification. Watch our video to learn more about strategies for TCI synthesis.